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Selected Patents

1. Penflufen Containing Compositions

EP 3 042 562 B1. The present invention relates to a composition containing penflufen and a potentiator selected from the group consisting of N,N-dimethyldodecylamine and cocoamine oxide, and uses thereof

2. ENHANCED PRESERVATIVE

US 10,721,934 B2. A composition having biocidal properties is disclosed. The composition includes a first biocide, optionally a second biocide, and a biocide enhancing agent. The first biocide may comprise an isothiazolin. The second biocide may comprise a pyrithione. The biocide enhancing agent may comprise an amine, an amine salt, an amine oxide, or mixtures thereof. The amine compound may have a carbon chain length of at least six carbon atoms, such as at least eight carbon atoms.

3. Coated metal pyrithione particles for treatment of microorganisms

Patent number: 8980235

Abstract: A composition comprising coated particles of a salt of pyrithione selected from the group consisting of monovalent and polyvalent pyrithione salts, and combinations thereof, partially or fully coated with a lipophilic agent. The composition is characterized by enhanced anti-fungal and anti-dandruff efficacy in shampoos. Also disclosed is a personal care composition, preferably a shampoo, containing a topical carrier and coated particles of a salt of pyrithione selected from the group consisting of monovalent and polyvalent pyrithione salts, and combinations thereof, partially or fully coated with a lipophilic agent.

Type: Grant

Filed: September 28, 2004

Date of Patent: March 17, 2015

Assignees: Arch Chemicals, Inc., The Proctor & Gamble Company

Inventors: Deqing Lei, George Polson, Diana T. Ciccognani, Kevin N. DiNicola, Richard B. Shalvoy, Katherine P. Roberts, Louis L. Punto, James Robert Schwartz, David Joseph Kaufman

 

4.Biocidal Compositions Comprising Iron Chelators

Publication number: 20140154189

Abstract: The present invention, therefore, is directed to an antimicrobial compositions that decreases the bioavailability of iron by introducing a higher-affinity iron-selective chelating agent capable of competing with microbial siderophores. In one aspect, the present invention relates to an antimicrobial composition including a potentiating antimicrobial composition including one or more antimicrobial agents and a chelator having a weight ratio of the antimicrobial agent to the chelator from about 1:1000 to about 1000:1.

Type: Application

Filed: October 14, 2013

Publication date: June 5, 2014

Applicant: Arch Chemicals, Inc.

Inventors: George Polson, Jody Jourden, Qi Zheng, Regina M. Prioli, Diana Ciccognani, Sungmee Choi

 

5. Chemical method of making a suspension, emulsion or dispersion of pyrithione particles

Patent number: 8709460

Abstract: A method for producing a suspension, emulsion or dispersion of de-agglomerated particles (advantageously submicron-sized particles) of pyrithione salts comprising contacting agglomerated pyrithione salt particles with a de-agglomerating agent to produce the desired de-agglomerated pyrithione salt particles. Also disclosed is a method for making de-agglomerated submicron-sized particles of pyrithione salts comprising a heating step. Also disclosed are the particles made by the above methods and compositions comprising the particles and a base medium.

Type: Grant

Filed: April 23, 2009

Date of Patent: April 29, 2014

Assignee: Arch Chemicals, Inc.

Inventors: Saeed M. Mohseni, Charles W. Kaufman, David C. Beaty, John J. Jardas, George Polson

 

6. Composition and Method For Preventing Discoloration of Pyrithione Containing Compositions

Publication number: 20140038933

Abstract: The present invention provides a composition containing a pyrithione compound and a pyranone compound and a method of reducing discoloration of compositions containing pyrithione compounds. The composition may be a soap composition.

Type: Application

Filed: July 30, 2013

Publication date: February 6, 2014

Applicant: Arch Chemicals, Inc.

Inventors: George Polson, Jody Jourden, Denise B. Taylor, Yongcheng Ji

 

7. Coated calcium hypochlorite composition

Patent number: 8252200

Abstract: The present invention is directed to a water treatment composition, comprising: calcium hypochlorite coated with a coating comprising at least one hydrated or anhydrous salt. The present invention is also directed to a water treatment composition, comprising: (a) an inner core layer comprising calcium hypochlorite; (b) one or more interlayers of selected salts positioned on top of said inner core layer, and (c) one or more outer layers of selected salts positioned on top of said interlayer(s).

Type: Grant

Filed: November 21, 2006

Date of Patent: August 28, 2012

Assignee: Arch Chemicals, Inc.

Inventors: Deqing Lei, George Polson, Sonia Oberson, Ellen M. Meyer, James D. Kilby

 

8. Composite biocidal particles

Patent number: 8158158

Abstract: A biocidal composition is disclosed comprising composite particles, each of said composite particles containing a shell and a core, said core comprising a metal or a metal-containing compound wherein the metal is a moiety selected from the group consisting of zinc, copper, bismuth, silver, zirconium, and combinations thereof said shell comprising a pyrithione adduct comprising the reaction product of pyrithione with a portion of said core metal or metal compound. In one aspect, an anti-fouling composition is disclosed comprising (a) an anti-soft-fouling effective amount of copper pyrithione; and (b) an anti-hard-fouling effective amount of a copper-containing salt, or oxide or hydroxide thereof. The present invention also relates to a method of making an anti-fouling composition comprising particles of copper pyrithione and a copper-containing salt that is effective against hard-fouling and soft-fouling organisms.

Type: Grant

Filed: February 15, 2002

Date of Patent: April 17, 2012

Assignee: Arch Chemicals, Inc.

Inventors: David F. Gavin, Craig Waldron, Robert J. Martin, George A. Polson

 

9. Composite biocidal particles

Patent number: 7942958

Abstract: A biocidal composition is disclosed comprising composite particles, each of the composite particles containing a shell and a core, the core comprising a metal or a metal-containing compound wherein the metal is a moiety selected from the group consisting of zinc, copper, bismuth, silver, zirconium, and combinations thereof, the shell comprising a pyrithione adduct comprising the reaction product of pyrithione with a portion of the core metal or metal compound. In one aspect, an anti-fouling composition is disclosed comprising (a) an anti-soft-fouling effective amount of copper pyrithione; and (b) an anti-hard-fouling effective amount of a copper-containing salt, or oxide or hydroxide thereof. The present invention also relates to a method of making an antifouling composition comprising particles of copper pyrithione and a copper-containing salt that is effective against hard-fouling and soft-fouling organisms.

Type: Grant

Filed: July 22, 1998

Date of Patent: May 17, 2011

Assignee: Arch Chemicals, Inc.

Inventors: David F. Gavin, Craig Waldron, Robert J. Martin, George A. Polson

 

10. Topical anti-microbial compositions

Patent number: 7674785

Abstract: Disclosed are topical compositions for the treatment of microbial infections on the skin or scalp which include a polyvalent metal salt of pyrithione and include a metal ion source. Also disclosed are methods for treating microbial infections of the skin or scalp using such compositions.

Type: Grant

Filed: December 8, 2005

Date of Patent: March 9, 2010

Assignees: The Procter & Gamble Company, Arch Chemicals, Inc.

Inventors: David Francis Gavin, Anthony Raymond Marchetta, John Daniel Nelson, Jr., George Polson, James Robert Schwartz, Patricia Aileen Turley

 

11. TOPICAL PYRITHIONE COMPOSITIONS AND METHODS FOR TREATMENT OF NAIL FUNGUS

Publication number: 20090298805

Abstract: Disclosed is a formulation and method for the treatment of fungal infections of the nail (onychomycosis) utilizing a topical composition comprising zinc pyrithione, a solubilizer for the zinc pyrithione, a film former, and a volatile solvent. The formulation is preferably in the form of a lacquer. The composition containing the metal pyrithione complex is topically applied to the infected nail preferably as a nail polish or lacquer which may be applied with a dropper, swab or the like to the afflicted nail surface. The treatment can be done at least two times a day, with a course of treatment lasting from several weeks to several months or until a cure is effected or a significant reduction of the infection is achieved.

Type: Application

Filed: June 3, 2008

Publication date: December 3, 2009

Inventors: George A. Polson, Katherine P. Roberts, Khat Kevin Lou, Kevin N. DiNicola

 

12. Chemical method of making a suspension, emulsion or dispersion of pyrithione particles

Publication number: 20090215739

Abstract: A method for producing a suspension, emulsion or dispersion of de-agglomerated particles (advantageously submicron-sized particles) of pyrithione salts comprising contacting agglomerated pyrithione salt particles with a de-agglomerating agent to produce the desired de-agglomerated pyrithione salt particles. Also disclosed is a method for making de-agglomerated submicron-sized particles of pyrithione salts comprising a heating step. Also disclosed are the particles made by the above methods and compositions comprising the particles and a base medium.

Type: Application

Filed: April 23, 2009

Publication date: August 27, 2009

Inventors: Saeed M. Mohseni, Charles W. Kaufman, David C. Beaty, John J. Jardas, George Polson

 

13. Chemical method of making a suspension, emulsion or dispersion of pyrithione particles

Patent number: 7544367

Abstract: A method for producing a suspension, emulsion or dispersion of de-agglomerated particles (advantageously submicron-sized particles) of pyrithione salts comprising contacting agglomerated pyrithione salt particles with a de-agglomerating agent to produce the desired de-agglomerated pyrithione salt particles. Also disclosed is a method for making de-agglomerated submicron-sized particles of pyrithione salts comprision a heating step. Also disclosed are the particles made by the above methods and compositions comprising the particles and a base medium.

Type: Grant

Filed: June 20, 2002

Date of Patent: June 9, 2009

Assignee: Arch Chemicals, Inc.

Inventors: Saeed M. Mohseni, Charles W. Kaufman, David C. Beaty, John J. Jardas, George Polson

 

14.Coated calcium hypochlorite composition

Publication number: 20070125979

Abstract: The present invention is directed to a water treatment composition, comprising: calcium hypochlorite coated with a coating comprising at least one hydrated or anhydrous salt. The present invention is also directed to a water treatment composition, comprising: (a) an inner core layer comprising calcium hypochlorite; (b) one or more interlayers of selected salts positioned on top of said inner core layer, and (c) one or more outer layers of selected salts positioned on top of said interlayer(s).

Type: Application

Filed: November 21, 2006

Publication date: June 7, 2007

Inventors: Deqing Lei, George Polson, Sonia Oberson, Ellen Meyer, James Kilby

 

 

15. Topical anti-microbial compositions

Publication number: 20060089342

Abstract: Disclosed are topical compositions for the treatment of microbial infections on the skin or scalp which include a polyvalent metal salt of pyrithione and include a metal ion source. Also disclosed are methods for treating microbial infections of the skin or scalp using such compositions.

Type: Application

Filed: December 8, 2005

Publication date: April 27, 2006

Inventors: David Gavin, Anthony Marchetta, John Nelson, George Polson, James Schwartz, Patricia Turley

 

16. Topical anti-microbial compositions

Patent number: 7026308

Abstract: Disclosed are topical compositions for the treatment of microbial infections on the skin or scalp which include a polyvalent metal salt of pyrithione and include a metal ion source. Also disclosed are methods for treating microbial infections of the skin or scalp using such compositions.

Type: Grant

Filed: June 22, 2000

Date of Patent: April 11, 2006

Assignees: The Procter & Gamble Company, Arch Chemicals, Inc.

Inventors: David Francis Gavin, Anthony Raymond Marchetta, John Daniel Nelson, Jr., George Polson, James Robert Schwartz, Patricia Aileen Turley

 

 

 

17. Coated metal pyrithione particles for treatment of microorganisms

Publication number: 20050118276

Abstract: A composition comprising coated particles of a salt of pyrithione selected from the group consisting of monovalent and polyvalent pyrithione salts, and combinations thereof, partially or fully coated with a lipophilic agent. The composition is characterized by enhanced anti-fungal and anti-dandruff efficacy in shampoos. Also disclosed is a personal care composition, preferably a shampoo, containing a topical carrier and coated particles of a salt of pyrithione selected from the group consisting of monovalent and polyvalent pyrithione salts, and combinations thereof, partially or fully coated with a lipophilic agent.

Type: Application

Filed: September 28, 2004

Publication date: June 2, 2005

Inventors: Deqing Lei, George Polson, Diana Ciccognani, Kevin DiNicola, Richard Shalvoy, Katherine Roberts, Louis Punto, James Schwartz, David Kaufman

 

18. Augmentation of pyrithione activity or a polyvalent metal salt of pyrithione activity by zinc-containing layered material

Publication number: 20040213751

Abstract: The present invention relates to a composition comprising an effective amount of pyrithione or a polyvalent metal salt of a pyrithione and an effective amount of a zinc-containing layered material which provides an augmentation factor greater than 1. The present invention further relates to a method of treating microbial infections, fungal infections, or treating dandruff comprising the use of a composition comprising an effective amount of pyrithione or a polyvalent metal salt of a pyrithione, an effective amount of a zinc-containing layered material which provides an augmentation factor greater than 1.

Type: Application

Filed: March 17, 2004

Publication date: October 28, 2004

Inventors: James Robert Schwartz, Eric Scott Johnson, Bonnie Theresa King, Joyce Ross Akred, George Polson, Patricia A. Turley

 

19. Use of materials having zinc ionophoric behavior

Publication number: 20040058855

Abstract: Disclosed is a method for delivering excess zinc to eukaryotic cells to inhibit the metabolism of the cell, the method comprising treating the cells with a zinc ionophoric that is capable of delivering a zinc ion across a cellular membrane wherein the minimum inhibitory concentration (MIC) of the zinc ionophoric material is less than about 500 ppm. Further disclosed is a method for delivering excess zinc to eukaryotic cells to inhibit the metabolism of the cell, the method comprising treating the cells with a zinc ionophoric material that is capable of delivering a zinc ion across a cellular membrane wherein the zinc ionophoric material is in combination with a zinc containing material and further wherein there is an increase in an intracellular zinc level by 1.5 fold more than would occur in the absence of the zinc ionophoric material.

Type: Application

Filed: March 18, 2003

Publication date: March 25, 2004

Inventors: James R. Schwartz, George Polson, Patricia A. Turley, John D. Nelson, David F. Gavin, Katherine P. Roberts, Carl Hinz Margraf, David Joseph Kaufman, Randall Glenn Marsh

 

20. Chemical method of making a suspension, emulsion or dispersion of pyrithione particles

Publication number: 20020197283

Abstract: A method for producing a suspension, emulsion or dispersion of de-agglomerated particles (advantageously submicron-sized particles) of pyrithione salts comprising contacting agglomerated pyrithione salt particles with a de-agglomerating agent to produce the desired de-agglomerated pyrithione salt particles. Also disclosed is a method for making de-agglomerated submicron-sized particles of pyrithione salts comprision a heating step. Also disclosed are the particles made by the above methods and compositions comprising the particles and a base medium.

Type: Application

Filed: June 20, 2002

Publication date: December 26, 2002

Inventors: Saeed M. Mohseni, Charles W. Kaufman, David C. Beaty, John J. Jardas, George Polson

 

21. Composite biocidal particles

Publication number: 20020110575

Abstract: A biocidal composition is disclosed comprising composite particles, each of said composite particles containing a shell and a core, said core comprising a metal or a metal-containing compound wherein the metal is a moiety selected from the group consisting of zinc, copper, bismuth, silver, zirconium, and combinations thereof said shell comprising a pyrithione adduct comprising the reaction product of pyrithione with a portion of said core metal or metal compound. In one aspect, an anti-fouling composition is disclosed comprising (a) an anti-soft-fouling effective amount of copper pyrithione; and (b) an anti-hard-fouling effective amount of a copper-containing salt, or oxide or hydroxide thereof. The present invention also relates to a method of making an anti-fouling composition comprising particles of copper pyrithione and a copper-containing salt that is effective against hard-fouling and soft-fouling organisms.

Type: Application

Filed: February 15, 2002

Publication date: August 15, 2002

Inventors: David F. Gavin, Craig Waldron, Robert J. Martin, George A. Polson

 

 

22. Chemical method of making a suspension, emulsion or dispersion of pyrithione particles

Patent number: 6432432

Abstract: A method for producing a suspension, emulsion or dispersion of de-agglomerated particles (advantageously submicron-sized particles) of pyrithione salts comprising contacting agglomerated pyrithione salt particles with a de-agglomerating agent to produce the desired de-agglomerated pyrithione salt particles. Also disclosed is a method for making de-agglomerated submicron-sized particles of pyrithione salts comprision a heating step. Also disclosed are the particles made by the above methods and compositions comprising the particles and a base medium.

Type: Grant

Filed: February 25, 2000

Date of Patent: August 13, 2002

Assignee: Arch Chemicals, Inc.

Inventors: Saeed M. Mohseni, Charles W. Kaufman, David C. Beaty, John J. Jardas, George Polson

23. Non-spherical and non-platelet forms of pyrithione salts and methods of making same

Patent number: 6242007

Abstract: The present invention relates to non-spherical and/or non-platelet pyrithione particles. Also disclosed is a method for producing non-spherical and/or non-platelet particles of pyrithione salts, comprising reacting pyrithione acid or a water-soluble salt of pyrithione and a water-soluble polyvalent metal salt in the presence of an ionic surfactant composition at temperature from about 20° C. to about 60° C. and at a pH from 4-9 to produce non-spherical and/or non-platelet particles of pyrithione salts. The present invention further relates to particles made by the above methods and products, such as shampoos, soaps, and skin-care medicaments made using these particles.

Type: Grant

Filed: October 1, 1999

Date of Patent: June 5, 2001

Assignee: Arch Chemicals, Inc.

Inventors: Saeed H. Mohseni, John J. Jardas, George Polson, David C. Beaty, Charles W. Kaufman

 

24. In-situ generation of zinc pyrithione in personal care compositions

Patent number: 6162446

Abstract: Disclosed is a personal care composition comprising: (a) water or an alcohol, (b) at least one dispersant or surfactant, and (c) as an antimicrobial or preservative additive, particles of an in-situ transchelation reaction product of a zinc compound selected from the group consisting of zinc salts of organic acids, zinc salts of inorganic acids, zinc hydroxide, zinc oxide, and combinations thereof, said zinc compound being soluble in said water or alcohol, with pyrithione acid or a pyrithione salt that is soluble in said water or alcohol. Also disclosed is a process for preparing the personal care composition, and a coated substrate containing a coating of the personal care composition.

Type: Grant

Filed: March 11, 1998

Date of Patent: December 19, 2000

Assignee: Arch Chemicals, Inc.

Inventors: Rahim Hani, George A. Polson

 

25. Method for producing particles of pyrithione salts and particles so produced

Patent number: 6017936

Abstract: The present invention relates to a method for producing submicron-sized particles of pyrithione salts, comprising reacting pyrithione or a water-soluble salt of pyrithione and a water-soluble polyvalent metal salt in a pressurized turbulent flow reactor that generates pulverizing forces, the reaction producing submicron sized particles of pyrithione salt. The present invention also relates to particles made by the above method, and products, such as shampoos, soaps, and skin care medicaments made using these particles.

Type: Grant

Filed: March 2, 1998

Date of Patent: January 25, 2000

Assignee: Arch Chemicals, Inc.

Inventors: George A. Polson, Richard H. Dumas, Rahim Hani

 

26. Non-spherical and non-platelet crystalline forms of pyrithione salts

Patent number: 6017562

Abstract: The present invention relates to non-spherical and/or non-platelet pyrithione particles. Also disclosed is a method for producing non-spherical and/or non-platelet particles of pyrithione salts, comprising reacting pyrithione or a water-soluble salt of pyrithione and a water-soluble polyvalent metal salt in the presence of a dispersant at a temperature from about 20.degree. C. to about 60.degree. C. to produce non-spherical and/or non-platelet particles of pyrithione salts. The present invention further relates to particles made by the above methods and products, such as shampoos, soaps, and skin-care medicaments made using these particles.

Type: Grant

Filed: February 18, 1998

Date of Patent: January 25, 2000

Assignee: Arch Chemicals, Inc.

Inventors: Charles W. Kaufman, Saeed H. Mohseni, John J. Jardas, George A. Polson, David C. Beaty

 

 CERTIFICATIONS